SALWA NIHAL . SYEDA SADIA FATIMA . KASHIF ABBASS . ABDUL SHAKOOR MEMON

ABSTRACT | Full Text Pdf

Background: Menopause and obesity are associated with hypo-vitaminosis D and osteopenia. Low body mass index (BMI) is a recognized risk factor for fragility fracture, whereas obesity is widely believed to be protective. The mechanisms by which increased body weight influences bone mass density (BMD) are still unknown. We investigated the impact of body mass index (BMI) status on the serum levels of vitamin D concentration and bone mineral density in pre and post-menopausal women.

Design: This cross-sectional study enrolled 94 healthy subjects. The participants were divided into two groups based on pre menopause and post-menopause.

Results: Females who were on the higher side of weight and BMI also had a higher BMD. Age, weight, serum calcium, BMI and BMD correlated significantly with each other while no relation was found between serum total vitamin D.

Conclusions: We observed stronger associations of weight, age, calcium and BMI with bone mineral density.