KASHIF ALI CHANNAR, ZAIB- UN- NISA, NARESH KUMAR, QADEER UL HASSAN, ABDUL BARI MEMON

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Objectives: The objective of this study was to determine the effect of dexamethasone in control of post-operative sequalae in surgical extraction of mandibular third molar surgery.

Methods: This study was a prospective double blind randomized control trail conducted in Department of Oral & Maxillofacial surgery, Liaquat University of Medical & Health sciences Hyderabad / Jamshoro from January 2011 to September 2012.All selected patients were divided into two groups by using random number table. Patients in Group- A were given dexamethasone 8 mg intramuscularly before surgery and 4 mg 24 hours after surgery and Co-Amoxiclave tablet 625mg BD and Ibuprofen 400 mg TDS and patients in group-B considered as control group were given Co-Amoxiclave 625 mg BD and Ibuprofen 400 mg TDS post operatively only for three days. The facial swelling and mouth opening were checked before surgery, and after 24 hours (1st day), after 48 hours (2nd day) and after 7 days. All the gathered information was noted and entered in a structured proforma

Results: The mean age of patients was 28.3 years in group A ,and in group B was 27.1 years. The most common impaction was mesioangular account for 45% of cases,followed by vertical, distoangular and horizantal impaction.The mean preoperative swelling was 210 in control group and 212 in steroid group. On 2nd day after surgery, post extraction swelling raised in both group and on 7thdays after surgery swelling reduced to 215 in control and 213 in steroid group. Statistically significant.

Conclusions: The use of dexamethasone appears to be a safe and effective method to reduce postoperative clinical symptoms in third molar surgery.