EFFECTIVENESS OF TELITHROMYCIN IN MANAGEMENT OF ACUTE PHARYNGITIS AND TONSILLITIS

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ABSTRACT: | Full Text PDF

OBJECTIVE: to evaluate the effectiveness of Telithromycin in the management of acute pharyngitis and tonsillitis.

DESIGN & DURATION: Prospective study conducted during Jan 2007 to Mar 2007.

SETTING: Outpatient department of Baitul Hikmah, Hamdard University and all irestigations & labouratory analysis was conducted at KMDC Karachi. MATERIAL AND

METHODS: This was a prospective and quasi experimental study. As far as the sample size is concerned, 40 patients fulfilling the inclusion criteria were included. A convenience sample from all consecutive patients clinically presenting with acute pharyngitis and tonsillitis were included. A six item questionnaire with various variables was used to record the parameters. The parameters included age (above 12 yrs), gender, dysphagia, inflammation of pharynx/tonsil, fever and cervical lymph node enlargement. Lactating and pregnant females were excluded from the study. Throat swab culture of all patients was assessed at day 0 and on 5the day after oral treatment with Telithromycin 800 mg once a day for five days.

CONCLUSION: Results of the study reveal that cure rate with Telithromycin for the treatment of bacterial pharyngitis and tonsillitis in our country is excellent as compared to those found treated with macrolides during other contemporary studies probably owing to development of resistance against them.

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