ABSTRACT: | Full Text PDF

OBJECT: To evaluate the effects of diclofenac sodium (NSAID) on Caecal Goblet cells of albino rats.

DESIGN: An animal study carried on experimental albino rats.

SETTING: An animal study carried out in the Department of Anatomy, Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Centre (JPMC), Karachi.

METHOD: Diclofenac sodium was administered to male albino Rats at a dose of 2 mg/ kg body weight orally once daily for two weeks. These animals were sacrificed, Caeca were identified and removed, opened along mesenteric border, fixed in alcoholic formalin, Embedded in paraplast, 4 um thick sections were cut on rotary microtome, stained with periodic acid Schiff