ABSTRACT: Full Text PDF

OBJECTIVE: Ghrelin is an appetite hormone activates food intake and participates in the regulation of energy homeostasis. Ghrelin and leptin levels are influenced by body fat. The aim of the study was to compare fasting ghrelin and leptin levels between obese and non-obese subjects and to investigate possible correlations of these peptide hormones with body mass index.

STUDY DESIGN: This was a prospective comparative study, conducted in the Department of Physiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi

SUBJECTS AND METHODS: Sixty subjects age range 22 to 52 years were included in this study. These subjects were divided in two groups according to body mass index (BMI). The 30 subjects age (36.50