ABSTRACT: Full Text PDF

BACKGROUND: Typhoid perforation of ileum is a grave problem seen in patients having typhoid fever. Various treatment modalities are there for repairing the typhoid ileal perforation. The objective of this study is to state our surgical experience and postoperative complications of treatment of typhoid ileal perforation.

METHODOLOGY: This prospective observational study was conducted in the Department of Surgery, Liaquat University of Medical Sciences and Hospital and a private hospital, Hyderabad from August 2007- July 2009. The patients with typhi dot and/or positive blood culture were included in this study after obtaining an informed consent. Patients with co-morbidities were excluded.

RESULTS: A total of 120 patients were operated for typhoid ileal perforation in the study period. There were 91 males (75.83%), 29 females (24.1%) with mean age of 21.43 years (17-38 years). Majority of patients were in 1st and 2nd decade of life. Seventy three patients (60.83%) had single perforation while rest of 47 patients (39.16%) had two or more perforations. Perforation was repaired in 93 patients (77.5%) while 27 patients (22.5 %) patients have resection anastomosis. wound infection was seen in 37 patients (30.83%) and wound dehiscence was seen in 8 patients (6.66%). Enterocutaneous Fistulae was seen in 17 patients (14.16%) Seven patients (5.83%) were died.

CONCLUSION: Typhoid ileal perforation is frequently reported in developing countries. A high postoperative complications rate was observed in this study. Aggressive resuscitation and prompt surgical intervention leads to decreased morbidity and mortality.